Alex Rodriguez launched a grand slam in the second inning, capping a seven-run frame, and the Yanks never looked back. Randy Johnson allowed one run in seven innings while Hideki Matsui hit a three-run homer and reached base in all six of his at-bats.
Frank Thomas hit a solo home run in his first official at-bat as a member of the A's, but it wasn't near enough as they collected just eight hits in an Opening Day loss. The Yankees touched left-hander Barry Zito for seven runs over 1 1/3 innings.
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