It's been more than a month.
Giants right-hander Matt Cain has been winless since May 15, looking to get back on track for a San Francisco team that has lost its touch of late, losing nine of 10 before a pair of victories over the D-backs ahead of Monday's homestand opener vs. the Padres at AT&T Park.
Cain is 0-2 with a 5.85 ERA in his last four starts, and overall he's just 1-5 on the year, with a 4.52 ERA in 63 2/3 innings.
His last start was his worst of the year. He surrendered eight runs (seven earned) on 10 hits, one walk and two home runs against the White Sox in Chicago. His ERA skyrocketed from 3.84 to its current mark.
Cain said after that start that his focus would be on his command.
"The biggest thing is just location," he said. "I just didn't maybe get [pitches] inside far enough or keep the ball down enough."
Cain was scheduled to start against Padres right-hander Andrew Cashner, but Cashner was scratched from the start late on Sunday for what was believed to be right shoulder soreness.
Cashner allowed just one run in seven innings in his previous start on June 18, outdueling Seattle ace Felix Hernandez.
Starting in Cashner's place will be right-hander Odrisamer Despaigne, who signed with the Padres in May and will be making his MLB debut.
This is the 27-year-old Cuban's first year in America. In seven starts between Double-A and Triple-A, Despaigne is 1-3 with a 6.03 ERA, 1.85 WHIP and 41 strikeouts in 31 1/3 innings. In his eight-year career in Cuba, he had a 3.65 ERA.
San Diego will need to make a move to clear a spot on the 40-man roster for him.
Padres: Byrnes relieved of duties
Before Sunday's Dodgers-Padres game, the Padres announced that general manager Josh Byrnes has been relieved of his duties.
Padres president and CEO Mike Dee said a search for a new general manager will begin immediately. In the interim, the general manager's duties will be split between senior vice president of baseball operations Omar Minaya and assistant general managers A.J. Hinch and Fred Uhlman Jr.
Byrnes, also the Padres' executive vice president, had been with the organization since December 2010, originally serving as the vice president of baseball operations under then-GM Jed Hoyer.
Dee said the change was based on the Padres' lackluster performance this season.
"This ownership group is committed to fielding a team that consistently competes for postseason play," Dee said. "Thus far this season, the results on the field have been mixed at best and clearly have not lived up to expectations. After a lengthy evaluation of every facet of our baseball operations, we have decided to make this change today."
Giants: Decisions looming on Pagan, Morse
Bad backs kept both Angel Pagan and Michael Morse out of San Francisco's outfield Sunday. Decisions will be made on both players' status when the team returns to San Francisco on Monday, manager Bruce Bochy said.
Pagan has missed a week with lower back stiffness, while Morse left Saturday's night's 6-4 Giants win over the D-backs with back tightness.
Both players are day to day, but Bochy didn't rule out the disabled list as a possibility for Pagan, who leads the team with a .307 batting average. However, Bochy said the Giants will look to avoid the DL as long as Pagan's condition improves.
"It hasn't been getting worse, and he's been doing baseball activities," Bochy said Sunday. "Morse is hoping to play tomorrow, but we'll wait until we get to San Francisco. I think tomorrow we'll have a pretty good idea on both of them."
Cain is 7-12 with a 3.04 ERA in 32 career starts against the Padres.
Michael Lananna is an associate reporter for MLB.com. This story was not subject to the approval of Major League Baseball or its clubs.