The Mets skipped Capuano's first turn through the rotation in order to give R.A. Dickey the opportunity to pitch the home opener on Friday, a 6-2 loss to the Nationals.
Now, it's Capuano's time to shine at Citi Field on Saturday at 7:10 p.m. ET. Washington will counter with Tom Gorzelanny.
"I feel great. Ready to go," Capuano said. "I felt good all spring. I felt healthy all spring. I felt like my command was pretty good for the most part. I couldn't have been happier with the way it went, so it was definitely a good lead-in to the season."
Capuano was available out of the bullpen for the first four games, and appeared once. He also threw 65-70 pitches on the side earlier this week to get physically ready for his start Saturday.
He's been mentally prepared for quite some time.
"I think I had some nerves in my first bullpen appearance -- I was kind of happy to get that first appearance out of the way," he said. "I'm just excited about this team. I think we've got a great group of guys, a potent offense, so I'm just excited to go out there and battle."
Gorzelanny is making his first start of the season for Washington. If Gorzelanny is feeling confident heading into the matchup, this is one reason why: The Mets' current roster is a combined 8-for-46 (.174) with no homers against the left-hander.
Nationals: Help available
The Nationals could activate right-hander Henry Rodriguez from the disabled list and recall right-hander Collin Balester if they need help in the bullpen.
The Nationals are 47-63 against the Mets since the franchise moved to Washington in 2005. They are 27-28 against the Mets in New York and won two series at Citi Field last season.Mets: Pagan moves back up
Mets manager Terry Collins shifted Angel Pagan back up to the second spot in the batting order. Pagan is a .302 career hitter batting second, and a .254 hitter batting fifth or sixth.
Thirteen of the club's next 16 games will be played at home. The Mets went 47-34 at Citi Field last season.
Look for Nationals catcher Wilson Ramos to see a majority of the action behind the plate going forward. Ivan Rodriguez will serve as his backup, the club said Friday.
Mets outfielder Jason Bay hit off a tee and did not feel any discomfort. Catcher Ronny Paulino has been cleared to begin baseball activities.